USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

Sara Lovisa, Valerie S. LeBleu, Björn Tampe et al. · Nature Medicine · 2015 · 982 citations · Full text

Medicine, Cell Biology, Nephrology +17

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

María T. Grande, Berta Sanchez‐Laorden, Cristina López-Blau et al. · Nature Medicine · 2015 · 801 citations · Full text

Medicine, Cell Biology, Pathology +10

USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development

Zhenghong Lin, Hee‐Young Yang, Qingfei Kong et al. · Molecular Cell · 2012 · 317 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

Ming Wang, Dan‐Qian Chen, Lin Chen et al. · British Journal of Pharmacology · 2018 · 165 citations · Full text

Medicine, Nephrology, Pharmacology +15

Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells

Victoria Gennaro, Timothy J. Stanek, Amy R. Peck et al. · Proceedings of the National Academy of Sciences · 2018 · 125 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17