Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells

Kaipeng Huang, Juan Huang, Xi Xie, +5

Free Radical Biology and Medicine

Signal TransductionSirt1 ResistsNrf2/are PathwayGlomerular Mesangial CellsImmunology +7

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells

Kaipeng Huang, Cheng Chen, Jie Hao, +4

Molecular and Cellular Endocrinology

InflammationFibrosisCell RegulationGrowth Factor-β1Immunology +7

The crosstalk between Sirt1 and Keap1/Nrf2/ARE anti-oxidative pathway forms a positive feedback loop to inhibit FN and TGF-β1 expressions in rat glomerular mesangial cells

Kaipeng Huang, Xiang Gao, Wentao Wei

Experimental Cell Research

Signal TransductionSignaling PathwayTgf-β1 ExpressionsFibroblast Growth FactorVascular Biology +7

Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy

Xi Xie, Jing Peng, Xiuting Chang, +6

Molecular and Cellular Endocrinology

UrologyRenal DiseaseMolecular PhysiologyKidney ResearchMedicine +9

Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling

Xi Xie, Xiuting Chang, Lei Chen, +6

Molecular and Cellular Endocrinology

BiochemistryMedicineDiabetesPharmacologyPhysiology +6

Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway

Juan Huang, Kaipeng Huang, Tian Lan, +4

Molecular and Cellular Endocrinology

InflammationSphk1-s1p Signaling PathwayMedicineDiabetesImmunology +9

Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells

Xi Xie, Jing Peng, Kaipeng Huang, +4

Molecular and Cellular Endocrinology

InflammationExperimental Diabetes-induced FibronectinDiabetesImmunologyDiabetic Kidney Disease +9

Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway

Jie Hao, Cheng Chen, Kaipeng Huang, +4

European Journal of Pharmacology

Metabolic SyndromeLipid MetabolismMedicineDiabetesMetabolic Regulation +8

Correction: Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models

Kaipeng Huang, Weihua Liu, Xie Xi, +6

PLoS ONE

Renal FunctionBiochemistryMedicineKidney FailureDiabetes +6

Sphingosine Kinase-1 Pathway Mediates High Glucose-Induced Fibronectin Expression in Glomerular Mesangial Cells

Tian Lan, Weihua Liu, Xi Xie, +8

Molecular Endocrinology

Renal PathologyGlomerular Mesangial CellsCellular PhysiologyGlomerulonephritisRenal Function +16