Epidemiological Features of Testicular Teratoma in a Prepubertal Population

Abstract

No AccessJournal of UrologyTestis1 Sep 1997Epidemiological Features of Testicular Teratoma in a Prepubertal Population Richard W. Grady, Jonathan H. Ross, and Robert Kay Richard W. GradyRichard W. Grady , Jonathan H. RossJonathan H. Ross , and Robert KayRobert Kay View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)64421-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Prepubertal teratomas of the testis are rare benign tumors. Knowledge of the epidemiology of testicular teratomas and associated alpha-fetoprotein (AFP) levels could assist in planning treatment for prepubertal patients suspected of having teratoma of the testis. Materials and Methods: We evaluated data on testicular teratoma from the Prepubertal Testis Tumor Registry of the Section on Urology of the American Academy of Pediatrics. Results: Median patient age at presentation was 13 months. Teratomas occurred equally in the right and left testes. Most patients presented with a scrotal mass. Preoperative AFP levels were elevated in 20 of the 34 patients and postoperative levels were elevated in 9 of 10. Most patients were treated with radical orchiectomy and no metastatic disease was reported. Conclusions: Data in the registry confirm the benign nature of this tumor. Normal AFP levels should not be expected in infants with teratoma. References 1 : Testicular sparing surgery for prepubertal teratoma of the testis: a clinical and pathological study.. J. Urol.1990; 144: 726. Abstract, Google Scholar 2 : Prepubertal testis tumor registry.. Urol. Clin. N. Amer.1993; 20: 1. Google Scholar 3 : Germinal testicular tumors in childhood. Report of observations and literature review.. Eur. Urol.1984; 10: 73. Google Scholar 4 : Teratomas and yolk sac tumors.. J. Clin. Path.1976; 29: 1021. Google Scholar 5 : Testicular tumors in prepubertal children.. Urology1979; 13: 581. Google Scholar 6 : Testicular tumors in children.. Amer. J. Surg.1965; 110: 876. Google Scholar 7 : A conservative approach to testicular tumors in children: 12 cases and their management.. J. Urol.1983; 129: 350. Abstract, Google Scholar 8 : Prepubertal testicular and paratesticular tumors. J. Urol.1996; 155: 392A. part 2, abstract 325. Google Scholar 9 : Serum alpha-fetoprotein (AFP) levels in normal infants.. Ped. Res.1981; 15: 50. Google Scholar 10 : Clinical Diagnosis and Management by Laboratory Methods. Philadelphia: W. B. Saunders Co.1996: 498. Google Scholar 11 : Tietz Textbook of Clinical Chemistry. Philadelphia: W. B. Saunders Co.1994: 2119. Google Scholar 12 : Yolk sac tumors and alpha-fetoprotein in first year of life.. Urology1993; 42: 79. Google Scholar 13 : Tumor markers in the management of urologic neoplasms.. AUA Update Series1987; vol. 6. lesson 36. Google Scholar 14 : Serum alpha-fetoprotein and gamma-G-globulin in the human conceptus.. J. Clin. Invest.1966; 45: 1825. Google Scholar 15 : Carcinoma in situ of the testis.. J. Urol.1989; 142: 243. Abstract, Google Scholar 16 : Intratubular germ cell neoplasia in testicular teratomas and epidermoid cysts.. Cancer1989; 64: 715. Google Scholar From the Section of Pediatric Urology, Department of Urology, Cleveland Clinic Foundation, Cleveland, Ohio.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited ByAgarwal P and Palmer J (2018) Testicular and Paratesticular Neoplasms in Prepubertal MalesJournal of Urology, VOL. 176, NO. 3, (875-881), Online publication date: 1-Sep-2006.SHUKLA A, WOODARD C, CARR M, HUFF D, CANNING D, ZDERIC S, KOLON T and SNYDER H (2018) Experience With Testis Sparing Surgery for Testicular TeratomaJournal of Urology, VOL. 171, NO. 1, (161-163), Online publication date: 1-Jan-2004.METCALFE P, FARIVAR-MOHSENI H, FARHAT W, McLORIE G, KHOURY A and BÄGLI D (2018) Pediatric Testicular Tumors: Contemporary Incidence and Efficacy of Testicular Preserving SurgeryJournal of Urology, VOL. 170, NO. 6, (2412-2416), Online publication date: 1-Dec-2003.VALLA J (2018) TESTIS-SPARING SURGERY FOR BENIGN TESTICULAR TUMORS IN CHILDRENJournal of Urology, VOL. 165, NO. 6 Part 2, (2280-2283), Online publication date: 1-Jun-2001.GARRETT J, CARTWRIGHT P, SNOW B and COFFIN C (2018) CYSTIC TESTICULAR LESIONS IN THE PEDIATRIC POPULATIONJournal of Urology, VOL. 163, NO. 3, (928-936), Online publication date: 1-Mar-2000. Volume 158Issue 3September 1997Page: 1191-1192 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.MetricsAuthor Information Richard W. Grady More articles by this author Jonathan H. Ross More articles by this author Robert Kay More articles by this author Expand All Advertisement PDF DownloadLoading ...