Publication | Closed Access
<i>Lactobacillus fermentum</i>F40-4 ameliorates hyperuricemia by modulating the gut microbiota and alleviating inflammation in mice
30
Citations
26
References
2023
Year
DysbiosisUa ExcretionImmunologyGut MicrobiotaProbioticsInflammationProbioticMicrobiota FunctionGut MicrobiologyGut-organ AxisIntestinal MicrobiotaHealth SciencesLiver PhysiologyMicrobiotaAlleviate HuaHost-microbe InteractionMicrobiomeMetabolomicsUa ProductionBiologyPhysiologyMicrobiologyMetabolismMedicine
L. fermentum F40-4 could inhibit UA synthetase activity in the liver to decrease UA production, promote expression level of UA excretion transporter NPT1 in the kidney and reshape microbiota in the gut to increase UA excretion, thereby alleviate HUA.
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