Concepedia

Design and syntheses of a bimolecular STING agonist based on the covalent STING antagonist

Ruochen Zang, Liang Xue, Meifang Zhang, Xiaoyue Peng, Xionghao Li, Kaixin Du, Chuanqin Shi, Yuqian Liu, Yuxi Lin, Wenwei Han,

European Journal of Medicinal Chemistry · 2023 · 16 citations · 43 references

DOI

Concepts

References

43

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

Seng‐Ryong Woo, Mercedes B. Fuertes, Leticia Corrales et al. · Immunity · 2014 · 1.8K citations · Full text

, , +12

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

Leticia Corrales, Laura Hix Glickman, Sarah M. McWhirter et al. · Cell Reports · 2015 · 1.5K citations · Full text

, , +17

Activated STING in a Vascular and Pulmonary Syndrome

Adriana A. de Jesus, Bernadette Marrero, Dan Yang et al. · New England Journal of Medicine · 2014 · 1.4K citations · Full text

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Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1.1K citations · Full text

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Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

Xu Zhang, Heping Shi, Jiaxi Wu et al. · Molecular Cell · 2013 · 1.1K citations · Full text

, , +10