Concepedia

2,2′,4,4′,5,5′-Hexabromophenyl ether (BDE-153) causes abnormal insulin secretion and disorders of glucose and lipid metabolism in mice

Zaoling Liu, Shu-Rui Jiang, Yong Fan, Jiasui Wang, Menglin Wang, Meiyan Li

Journal of the Chinese Medical Association · 2023 · 12 citations · 12 references

Open access

Abstract

Our results suggest that BDE-153 may interfere with the expression of adipokines and the secretion of insulin by affecting the expression of PPARγ and AMPKα, which play a key role in glucose and lipid metabolism, leading to the occurrence of glucose and lipid metabolism disorder.

References

12

Prenatal Exposure to the Environmental Obesogen Tributyltin Predisposes Multipotent Stem Cells to Become Adipocytes

Séverine Kirchner, Tiffany Kieu, Connie Chow et al. · Molecular Endocrinology · 2010 · 289 citations · Full text

Adipose Mass, Oxidative Stress, Obesity +16

Association of Brominated Flame Retardants With Diabetes and Metabolic Syndrome in the U.S. Population, 2003–2004

Jisun Lim, Duk‐Hee Lee, David R. Jacobs · Diabetes Care · 2008 · 198 citations · Full text

Ligand Binding and Activation of PPAR γ by Firemaster ® 550: Effects on Adipogenesis and Osteogenesis in Vitro

Hari K. Pillai, Mingliang Fang, Dmitri Beglov et al. · Environmental Health Perspectives · 2014 · 196 citations · Full text

Spatiotemporal distribution, source apportionment and ecological risk assessment of PBDEs and PAHs in the Guanlan River from rapidly urbanizing areas of Shenzhen, China

Xinxiu Liang, Muhammad Junaid, Zhifen Wang et al. · Environmental Pollution · 2019 · 82 citations

Spatiotemporal Distribution, River Basin Management, Guanlan River +11

Polybrominated Diphenyl Ethers (PBDEs) in Paired Human Hair and Serum from e-Waste Recycling Workers: Source Apportionment of Hair PBDEs and Relationship between Hair and Serum

Jing Zheng, Ke-Hui Chen, Xiao‐Jun Luo et al. · Environmental Science & Technology · 2013 · 66 citations