Kidney Disease Progression in Membranous Nephropathy among Black Participants with High-Risk APOL1 Genotype

Abstract

The prevalence of high-risk APOL1 variant among Black membranous nephropathy participants is comparable with the general Black population (10%-15%), yet the high-risk genotype was associated with worse eGFR decline and faster time to kidney failure compared with low-risk genotype and participants that were not Black.