Concepedia

Publication | Open Access

Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma

DOIFull Paper Access

43

Citations

36

References

2023

Year

Salvador Alejo, Bridgitte E. Palacios, Prabhakar Pitta Venkata, Yi He, Wenjing Li, Jessica D. Johnson, Yihong Chen, Sridharan Jayamohan, Uday P. Pratap, K. Clarke,
Neuro-Oncology

Abstract

Our results provide evidence that KDM1A inhibition sensitizes GBM to TMZ via attenuation of DNA DSB repair pathways.

References

YearCitations

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