Discovery of a first-in-class orally available HBV cccDNA inhibitor

ChEA3: transcription factor enrichment analysis by orthogonal omics integration

Alexandra Keenan, Denis Torre, Alexander Lachmann et al. · Nucleic Acids Research · 2019 · 1.2K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

Julie Lucifora, Yuchen Xia, Florian Reisinger et al. · Science · 2014 · 874 citations · Full text

Pharmacy, Molecular Biology, Molecular Medicine +17

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function

Laura Belloni, Teresa Pollicino, Francesca De Nicola et al. · Proceedings of the National Academy of Sciences · 2009 · 490 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound

Jie Wang, Tao Shen, Xiangbo Huang et al. · Journal of Hepatology · 2016 · 445 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Structural organization of the hepatitis B virus minichromosome

C.–Thomas Bock, Susanne Schwinn, Stephen Locarnini et al. · Journal of Molecular Biology · 2001 · 355 citations

Life Sciences, Molecular Biology, Molecular Genetics +14