Concepedia

An integrated strategy to study the combination mechanisms of Bupleurum chinense DC and Paeonia lactiflora Pall for treating depression based on correlation analysis between serum chemical components profiles and endogenous metabolites profiles

Congcong Chen, Junshen Tian, Xiaoxia Gao, Xuemei Qin, Guanhua Du, Yuzhi Zhou

Journal of Ethnopharmacology · 2022 · 16 citations · 27 references

DOI

Concepts

References

27

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

Vicky Lampropoulou, Alexey Sergushichev, Monika Bambousková et al. · Cell Metabolism · 2016 · 1.5K citations · Full text

, , +16

Traditional Chinese medicine

Jinling Tang, Baoyan Liu, Kan-Wen Ma · The Lancet · 2008 · 863 citations

Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis

Monika Bambousková, Laurent Gorvel, Vicky Lampropoulou et al. · Nature · 2018 · 724 citations

, , +14

<scp>d</scp> -Amino acid oxidase controls motoneuron degeneration through <scp>d</scp> -serine

Jumpei Sasabe, Yurika Miyoshi, Masataka Suzuki et al. · Proceedings of the National Academy of Sciences · 2011 · 202 citations · Full text

, , +17