Bone marrow stromal cell‐derived exosomal circular RNA improves diabetic foot ulcer wound healing by activating the nuclear factor erythroid 2‐related factor 2 pathway and inhibiting ferroptosis

Abstract

Exosomal circ-ITCH from BMSCs inhibited ferroptosis and improved the angiogenesis of HUVECs through activation of the Nrf2 signalling pathway by recruiting TAF15 protein, ultimately accelerating the wound healing process in DFU.