Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Paul M. Ridker, Tom Thurén, Jean MacFadyen, +24

New England Journal of Medicine

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

Alan Daugherty, J. Lawrence Dunn, Debra L. Rateri, +1

Journal of Clinical Investigation

Vascular DiseaseLipid PeroxidationImmunologyHuman Atherosclerotic LesionsRedox Biology +16

Low-Dose Methotrexate for the Prevention of Atherosclerotic Events

Paul M. Ridker, Brendan M. Everett, Aruna D. Pradhan, +23

New England Journal of Medicine

Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

Seigo Sugiyama, Yoshikatsu Okada, Galina K. Sukhova, +3

American Journal Of Pathology

InflammationThrombosisVascular DiseaseCardiovascular DiseaseGranulocyte +13

Neutrophil Infiltration of Culprit Lesions in Acute Coronary Syndromes

Takahiko Naruko, Makiko Ueda, Kazuo Haze, +12

Circulation

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

Linda Hazell, L. Arnold, Dave Flowers, +3

Journal of Clinical Investigation

Hocl AggregatesLipid PeroxidationImmunologyHypochlorite-modified ProteinsHocl-modified Proteins +14

Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction

Kaspar Broch, Anne Kristine Anstensrud, Sindre Woxholt, +20

Journal of the American College of Cardiology

InflammationThrombosisCardiovascular DiseaseAtherosclerosisInterleukin-6 Receptor Inhibition +8

Measuring Myeloperoxidase Activity in Biological Samples

Benjamin Pulli, Muhammad Ali, Reza Forghani, +5

PLoS ONE

Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide

Heather A. Parker, Amelia M. Albrett, Anthony J. Kettle, +1

Journal of Leukocyte Biology

Increased atherosclerosis in myeloperoxidase-deficient mice

Marie‐Luise Brennan, Melissa M. Anderson, Diana M. Shih, +10

Journal of Clinical Investigation