Concepedia

In Silico Study of Entry Inhibitor from Moringa oleifera Bioactive Compounds against SARS-CoV-2 Infection

Nala Mawaddani, Ekris Sutiyanti, Muhammad Hermawan Widyananda, Viol Dhea Kharisma, Dora Dayu Rahma Turista, Muhammad Badrut Tamam, Vikash Jakhmola, Syamsurizal Syamsurizal S, Bayu Ramadhani Fajri, Muhammad Raffi Ghifari,

Pharmacognosy Journal · 2022 · 18 citations · 31 references

DOIFull text

Open access

Concepts

Abstract

] M. oleifera was the most appropriate candidate for an antiviral agent against SARS-CoV-2. The aim of this study was to screen bioactive compounds of Moringa oleifera and to identify the antiviral potential compounds toward SARS-CoV-2 through an entry inhibitor mechanism.

References

31

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Zhenming Jin, Xiaoyu Du, Yechun Xu et al. · Nature · 2020 · 4.5K citations · Full text

, , +10

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

, , +17

Remdesivir Strongly Binds to Both RNA-Dependent RNA Polymerase and Main Protease of SARS-CoV-2: Evidence from Molecular Simulations

Hoang Linh Nguyen, Nguyen Quoc Thai, Duc Toan Truong et al. · The Journal of Physical Chemistry B · 2020 · 87 citations · Full text

, , +17

Molecular docking study of sea urchin (Arbacia lixula) peptides as multi-target inhibitor for non-small cell lung cancer (NSCLC) associated proteins

Muhammad Hermawan Widyananda, Setyaki Kevin Pratama, Rizky Senna Samoedra et al. · Journal of Pharmacy & Pharmacognosy Research · 2021 · 85 citations · Full text

, , +17

Herbal combination from Moringa oleifera Lam. and Curcuma longa L. as SARS-CoV-2 antiviral via dual inhibitor pathway: A viroinformatics approach

Viol Dhea Kharisma, Aggy Agatha, Arif Nur Muhammad Ansori et al. · Journal of Pharmacy & Pharmacognosy Research · 2022 · 84 citations · Full text

, , +17