CD248 induces a maladaptive unfolded protein response in diabetic kidney disease

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

Marcella A. Calfon, Huiqing Zeng, Fumihiko Urano et al. · Nature · 2002 · 2.9K citations

Life Sciences, Cell Biology, Molecular Biology +5

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

Ann–Hwee Lee, Neal N. Iwakoshi, Laurie H. Glimcher · Molecular and Cellular Biology · 2003 · 2.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

Arthur Kaser, Ann–Hwee Lee, André Franke et al. · Cell · 2008 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Adaptation to ER Stress Is Mediated by Differential Stabilities of Pro-Survival and Pro-Apoptotic mRNAs and Proteins

D. Thomas Rutkowski, Stacey Arnold, Corey N. Miller et al. · PLoS Biology · 2006 · 797 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The single-cell transcriptomic landscape of early human diabetic nephropathy

Parker C. Wilson, Yuhei Kirita, Kohei Uchimura et al. · Proceedings of the National Academy of Sciences · 2019 · 544 citations · Full text

Life Sciences, Molecular Biology, Nephrology +17