Concepedia

PITTching in for lysosome repair

Claire S. Goul, Roberto Zoncu

Developmental Cell · 2022 · 11 citations · 8 references

DOI

Concepts

References

8

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Ikuko Maejima, Atsushi Takahashi, Hiroko Omori et al. · The EMBO Journal · 2013 · 639 citations · Full text

, , +16

Triggered recruitment of ESCRT machinery promotes endolysosomal repair

Michael L. Skowyra, Paul H. Schlesinger, Teresa V. Naismith et al. · Science · 2018 · 550 citations

, , +16

ATG2 transports lipids to promote autophagosome biogenesis

Diana P. Valverde, Shenliang Yu, Nikit Kumar et al. · The Journal of Cell Biology · 2019 · 548 citations · Full text

, , +15

ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival

Maja Radulovic, Kay Oliver Schink, Eva M. Wenzel et al. · The EMBO Journal · 2018 · 438 citations · Full text

, , +11

A phosphoinositide signalling pathway mediates rapid lysosomal repair

Xiaojun Tan, Toren Finkel · Nature · 2022 · 365 citations · Full text

, , +12