Concepedia

Design, synthesis and biological evaluation of novel pyrazinone derivatives as PI3K/HDAC dual inhibitors

Zi-Xiao Wang, Shuai Wang, Xue-Peng Qiao, Wenbo Li, Jian-Tao Shi, Yiru Wang, Shi‐Wu Chen

Bioorganic & Medicinal Chemistry · 2022 · 17 citations · 23 references

DOIFull text

Open access

Concepts

References

23

Cell Sensitivity Assays: The MTT Assay

Johan van Meerloo, Gertjan J.L. Kaspers, Jacqueline Cloos · Methods in molecular biology · 2011 · 2.5K citations

, , +9

HDAC6 is a microtubule-associated deacetylase

Charlotte Hubbert, Amaris R. Guardiola, Rong Shao et al. · Nature · 2002 · 2.4K citations

, , +5

Jaguar: A high‐performance quantum chemistry software program with strengths in life and materials sciences

Arteum D. Bochevarov, Edward Harder, Thomas F. Hughes et al. · International Journal of Quantum Chemistry · 2013 · 1.8K citations · Full text

, , +14

Computer-aided drug design platform using PyMOL

Markus A. Lill, Matthew L. Danielson · Journal of Computer-Aided Molecular Design · 2010 · 636 citations

, , +10

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors

Charlotte Bradbury, Farhat L. Khanim, Rachel Hayden et al. · Leukemia · 2005 · 401 citations

, , +13