Concepedia

The therapeutic window of antibody drug conjugates: A dogma in need of revision

Raffaele Colombo, Jamie R. Rich

Cancer Cell · 2022 · 180 citations · 6 references

DOI

Concepts

References

6

Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer

Shanu Modi, William Jacot, Toshinari Yamashita et al. · New England Journal of Medicine · 2022 · 2.5K citations · Full text

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Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer

New England Journal of Medicine · 2022 · 1.1K citations · Full text

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Preclinical safety profile of trastuzumab emtansine (T-DM1): Mechanism of action of its cytotoxic component retained with improved tolerability

Kirsten Achilles Poon, Kelly M. Flagella, Joseph C. Beyer et al. · Toxicology and Applied Pharmacology · 2013 · 194 citations · Full text

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Human and mouse albumin bind their respective neonatal Fc receptors differently

Jeannette Nilsen, Malin Bern, Kine Marita Knudsen Sand et al. · Scientific Reports · 2018 · 73 citations · Full text

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Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

Clinical Cancer Research · 2022 · 72 citations · Full text

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