Nanoparticle-enabled concurrent modulation of phagocytosis and repolarization of macrophages for enhanced cancer immunotherapy

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

Stephen B. Willingham, Jens-Peter Volkmer, Andrew J. Gentles et al. · Proceedings of the National Academy of Sciences · 2012 · 1.7K citations · Full text

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CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

Siddhartha Jaiswal, Catriona Jamieson, Wendy W. Pang et al. · Cell · 2009 · 1.6K citations

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CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin’s Lymphoma

Ranjana H. Advani, Ian W. Flinn, Leslie Popplewell et al. · New England Journal of Medicine · 2018 · 1.1K citations · Full text

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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Christopher B. Rodell, Sean P. Arlauckas, Michael F. Cuccarese et al. · Nature Biomedical Engineering · 2018 · 1.1K citations

Medicine, Immunology, Oncology +16

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

Qian Chen, Chao Wang, Xudong Zhang et al. · Nature Nanotechnology · 2018 · 1K citations

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