Biomaterials Science · 2022 · 50 citations · 38 references
Life SciencesCancer BiologyCell BiologyBiomaterialsDrug DeliveryTumor Microenvironment3D BioprintingCell MigrationExtracellular MatrixHydrogel BiomaterialsHydrogelsTumor Invasion3D Cell Culture Models3D Tumor ModelsCancer Cell MigrationCell Migration DynamicsCell Migration Through MatrixCell-extracellular Matrix InteractionsDrug ScreeningMigration Through Three-dimensional Matrices
and real-time measurement of cell movement, (iii) detailed molecular analysis for the study of mechanisms underlying cell migration and invasion, and (iv) the identification of novel therapeutic options. This work demonstrates that this HTP 3D bioprinted cell migration platform has broad applications across quantitative cell and cancer biology as well as drug screening.
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Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Kandice R. Levental, Hongmei Yu, Laura Kass et al. · Cell · 2009 · 4K citations · Full text
Matthias P. Lütolf, Janelle L. Lauer‐Fields, Hugo G. Schmoekel et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text