A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability

MoonSun Jung, Joanna N. Skhinas, Eric Y. Du, M. A. Kristine Tolentino, Robert H. Utama, Martin Engel, Alexander Volkerling, Andrew Sexton, Aidan P. O’Mahony, Julio Ribeiro,

Biomaterials Science · 2022 · 50 citations · 38 references

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Abstract

and real-time measurement of cell movement, (iii) detailed molecular analysis for the study of mechanisms underlying cell migration and invasion, and (iv) the identification of novel therapeutic options. This work demonstrates that this HTP 3D bioprinted cell migration platform has broad applications across quantitative cell and cancer biology as well as drug screening.

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38