Concepedia

Leptin-depended NLRP3 inflammasome activation in osteoarthritic chondrocytes is mediated by ROS

Evanthia Mourmoura, Varvara Trachana, Alexandra Tsoumpou, Andreas Goutas, Aliki-Alexandra Papageorgiou, Nikolaos Stefanou, Aspasia Tsezou

Mechanisms of Ageing and Development · 2022 · 16 citations · 57 references

DOI

Concepts

References

57

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

François Ghiringhelli, Lionel Apétoh, Antoine Tesnière et al. · Nature Medicine · 2009 · 1.8K citations · Full text

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Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies

Aiyong Cui, Huizi Li, Dawei Wang et al. · EClinicalMedicine · 2020 · 1.6K citations · Full text

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NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation

Lena Serrander, Laetitia Cartier, Karen Bedard et al. · Biochemical Journal · 2007 · 620 citations · Full text

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Evidence for a key role of leptin in osteoarthritis

Hélène Dumond, Nathalie Presle, Bernard Terlain et al. · Arthritis & Rheumatism · 2003 · 562 citations

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Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism

Xingyong Wan, Chengfu Xu, Yiming Lin et al. · Journal of Hepatology · 2015 · 363 citations

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