Epithelial cell‐expressed type <scp>II IL</scp>‐4 receptor mediates eosinophilic esophagitis

Abstract

We demonstrate a definitive role for IL-13 signaling via IL-13Rα1 in EoE. These data provide mechanistic insights into the mode of action of current therapies in EoE and highlight the type II IL-4R as a future therapeutic target.