Biochemical Pharmacology · 2022 · 23 citations · 36 references
MedicineBiochemistryPharmacologyCell SignalingHepatologyCholestatic Liver Disease TherapyCholestatic Liver InjuryCirrhosisHepatic PathophysiologyHepatotoxicity MechanismsLiver DiseaseCholestasis PathophysiologyHepatoprotective AgentsInflammation Modulation In CholestasisLiver Injury MechanismsLiver Injury ResponsePregnane X Receptor Signaling
36
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature · 2016 · 3.2K citations · Full text
Pore-forming activity and structural autoinhibition of the gasdermin family
Jingjin Ding, Kun Wang, Wang Liu et al. · Nature · 2016 · 2.8K citations
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi et al. · Nature · 2011 · 2.5K citations
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Wanting He, Haoqiang Wan, Lichen Hu et al. · Cell Research · 2015 · 2.5K citations · Full text