Targeting Plk1 Sensitizes Pancreatic Cancer to Immune Checkpoint Therapy - Concepedia

Concepedia

Publication | Open Access

Targeting Plk1 Sensitizes Pancreatic Cancer to Immune Checkpoint Therapy

DOI Full Paper Access

67

Citations

30

References

2022

Year

Zhuangzhuang Zhang, Lijun Cheng, Jie Li, Qi Qiao, Anju Karki, Derek B. Allison, Nuha Shaker, Kunyu Li, Sagar M. Utturkar, Nadia A. Lanman,

Cancer Research

Abstract

Inhibition of Plk1 induces upregulation of PD-L1 expression in pancreatic ductal adenocarcinoma, stimulating antitumor immunity and sensitizing tumors to immunotherapy.

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