Pentagalloylglucose disrupts the PALB2-BRCA2 interaction and potentiates tumor sensitivity to PARP inhibitor and radiotherapy

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The role of radiotherapy in cancer treatment

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Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

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Life Sciences, Molecular Biology, Molecular Genetics +15

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

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PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

Feng Zhang, Jianglin Ma, Jiaxue Wu et al. · Current Biology · 2009 · 553 citations · Full text

Life Sciences, Genetics, Molecular Biology +14