Concepedia

Interleukin-6 and tumor necrosis factor-α attenuate dopamine release in mice fed a high-fat diet, but not medium or low-fat diets

Heather A. Emmons, Conner W. Wallace, Steve C. Fordahl

Nutritional Neuroscience · 2022 · 10 citations · 50 references

DOIFull text

Open access

Concepts

Abstract

. Overall, these data provide evidence that dietary fat increases neural responsiveness to cytokines, which may help inform comorbidities between diet-induced obesity and depression or other mood disorders.

References

50

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

, , +17

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Gökhan S. Hotamışlıgil, Pascal Peraldi, Adriane I. Budavari et al. · Science · 1996 · 2.6K citations

, , +17

Protection from obesity-induced insulin resistance in mice lacking TNF-α function

K. Teoman Uysal, Sarah M. Wiesbrock, Michael W. Marino et al. · Nature · 1997 · 2.2K citations

, , +14

Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects

Victoria Rotter, Ivan Nagaev, Ulf Smith · Journal of Biological Chemistry · 2003 · 1K citations · Full text

, , +17

Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance

Daniela Miti Lemos Tsukumo, Carvalho Filho, José Barreto Campello Carvalheira et al. · Diabetes · 2007 · 817 citations · Full text

, , +17