Concepedia

Publication | Open Access

A discovery of clinically approved Panlongqi Tablet for repositioning to treat osteoarthritis by inhibiting PI3K/AKT activation

DOIFull Paper Access

16

Citations

20

References

2022

Year

Lu Wang, Panyu Xu, Ying Xu, Ruiqin Cui, Yibo Yang, Zhao Zou, Hanqian Du, Chunyan Zhu, Guoxin Zhang, Tengfei Han,
Phytomedicine

Abstract

PLQT exerted pharmacological effects on the key pathological links of osteoarthritis including chondrocyte apoptosis, extracellular matrix degradation, inflammation, and subchondral bone metabolism by inhibiting the TLR4-RAC1-PIK3CA-Akt-NFκB axis-related proteins.

References

YearCitations

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