Cell Reports Medicine · 2022 · 57 citations · 51 references
Life SciencesCell BiologyMolecular BiologyGene ExpressionInflammationMolecular Cell BiologyAdipocyte DifferentiationCell-cell Communication AnalysisInflammatory SignalingOcular InflammationSingle-cell Rna Sequencing AnalysisSingle-cell TranscriptomicsCell-cell Communication Pathway AnalysisOrbital AdipogenesisPeriocular Tissue ChangesResident Tissue MacrophagesSingle-cell Gene Expression ProfilingSingle-cell Rna SequencingSingle-cell Transcriptomic Communication Analysis
cytotoxic T lymphocytes with the terminal differentiation phenotype to be another source of interferon-γ, a molecule actively engaging in TAO pathogenesis. Cell-cell communication analysis reveals increased activity of CXCL8/ACKR1 and TNFSF4/TNFRSF4 interactions in TAO. This study provides a comprehensive local cell landscape of TAO and may be valuable for future therapy investigation.
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Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
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Fast, sensitive and accurate integration of single-cell data with Harmony
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