Metagenomic profiling of ocular surface microbiome changes in Demodex blepharitis patients

Abstract

Proteobacteria's increased prevalence may indicate ocular microbial community instability. The species <i>Sphingobium</i> sp. <i>YG1</i> and <i>Acinetobacter guillouiae</i> are potentially pathogenic bacterial biomarkers in DB. <i>Demodex</i> infection mainly affects the ocular surface microbiome rather than penetrating deeper into the meibomian gland.