Theacrine ameliorates experimental liver fibrosis in rats by lowering cholesterol storage via activation of the Sirtuin 3-farnesoid X receptor signaling pathway

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis

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Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

Jean‐Philippe Pradère, Johannes Kluwe, Samuele De Minicis et al. · Hepatology · 2013 · 597 citations · Full text

Life Sciences, Immunology, Pathology +17

Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

Kengo Tomita, Toshiaki Teratani, Takahiro Suzuki et al. · Hepatology · 2013 · 309 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Antiatherosclerotic effect of farnesoid X receptor

Andrea Mencarelli, Barbara Renga, Eleonora Distrutti et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2008 · 199 citations

Medicine, Cardiology, Pharmacology +17

SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity

Tian Zhang, Jingxin Liu, Shengnan Shen et al. · Cell Death and Differentiation · 2019 · 178 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16