Concepedia

<sup>19</sup>F chemical library and <sup>19</sup>F-NMR for a weakly bound complex structure

Shoko Shinya, Ritsuko Katahira, Kyoko Furuita, Toshihiko Sugiki, Young‐Ho Lee, Yoshikazu Hattori, Kohei Takeshita, Atsushi Nakagawa, Aoi Kokago, Ken‐ichi Akagi,

RSC Medicinal Chemistry · 2022 · 11 citations · 21 references

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Concepts

Abstract

19 F-NMR analysis using the optimized 19 F chemical library enables the modeling of the structure of the weakly bound protein–compound complex, overcoming the difficulty in fragment-based drug discovery.

References

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