Differentiation of iPS-Cells into Peripheral Sensory Neurons

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

Stuart M. Chambers, Yuchen Qi, Yvonne Mica et al. · Nature Biotechnology · 2012 · 620 citations · Full text

Life Sciences, Cell Biology, Neuroscience +16

Defining the Functional Role of NaV1.7 in Human Nociception

Lucy McDermott, Greg A. Weir, Andreas C. Themistocleous et al. · Neuron · 2019 · 208 citations · Full text

Medicine, Neurobiology, Neuroscience +8

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

Lishuang Cao, Aoibhinn McDonnell, Anja Nitzsche et al. · Science Translational Medicine · 2016 · 199 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology

Cédric Bardy, Mark van den Hurk, Boyko Kakaradov et al. · Molecular Psychiatry · 2016 · 168 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

Gareth T. Young, Alex Gutteridge, Heather DE Fox et al. · Molecular Therapy · 2014 · 147 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17