TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling

Peng Peng, Hongtao Zhu, Dan Liu, Zirong Chen, Xiaolin Zhang, Zhongyin Guo, Minhai Dong, Li‐Jun Wan, Po Zhang, Guohao Liu,

Theranostics · 2022 · 134 citations · 59 references

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Abstract

TAM-derived TGFBI promotes GSC-driven tumor growth through integrin αvβ5-Src-Stat3 signaling. High serum or CSF TGFBI may serve as a potential diagnostic and prognostic bio-index for GBMs.

References

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