Concepedia

Publication | Open Access

Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology

DOIFull Paper Access

76

Citations

38

References

2022

Year

Camila M. Silva, Carlos W. Wanderley, Flávio P. Veras, Augusto V. Gonçalves, Mikhael Haruo Fernandes de Lima, Juliana E. Toller-Kawahisa, Giovanni Freitas Gomes, Daniele C. Nascimento, Valter Silva Monteiro, Isadora Marques Paiva,
Critical Care

Abstract

These results demonstrated that GSDMD-dependent NETosis plays a critical role in COVID-19 immunopathology and suggests GSDMD as a novel potential target for improving the COVID-19 therapeutic strategy.

References

YearCitations

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