Molecular signatures and cellular diversity during mouse habenula development

Lieke L. van de Haar, Danai Riga, Juliska E. Boer, Oxana Garritsen, Youri Adolfs, Thomas E. Sieburgh, Roland E. van Dijk, Kyoko Watanabe, Nicky C.H. van Kronenburg, Mark H. Broekhoven,

Cell Reports · 2022 · 17 citations · 70 references

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Abstract

habenula neurons. Finally, we show how comparison of single-cell transcriptional profiles and GWAS data links specific developing habenular subtypes to psychiatric disease. Together, our study begins to dissect the mechanisms underlying habenula neuron subtype-specific development and creates a framework for further interrogation of habenular development in normal and disease states.

References

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