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Investigation of Functional Synergism of CENPF and FOXM1 Identifies POLD1 as Downstream Target in Hepatocellular Carcinoma

Daniel Wai‐Hung Ho, Wai-Ling Macrina Lam, Lo‐Kong Chan, Irene Oi‐Lin Ng

Frontiers in Medicine · 2022 · 15 citations · 16 references

DOIFull text

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Abstract

Taken together, our data suggest that CENPF and FOXM1 could synergistically support hepatocarcinogenesis via the regulation of POLD1. CENPF and FOXM1 may represent new vulnerabilities to novel drug-based therapy in HCC.

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