Concepedia

TFAM downregulation promotes autophagy and ESCC survival through mtDNA stress-mediated STING pathway

Yujia Li, Qi Yang, Hui Chen, Xiaotian Yang, Jingru Han, Xiaojuan Yao, Xiajie Wei, Jiaoyang Si, Huanling Yao, Hongliang Liu,

Oncogene · 2022 · 65 citations · 26 references

DOI

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26

Mitochondrial DNA stress primes the antiviral innate immune response

A. Phillip West, William Khoury-Hanold, Matthew Staron et al. · Nature · 2015 · 1.9K citations · Full text

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STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

Seng‐Ryong Woo, Mercedes B. Fuertes, Leticia Corrales et al. · Immunity · 2014 · 1.8K citations · Full text

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PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

Valerie S. LeBleu, Joyce T. O’Connell, Karina N. Gonzalez Herrera et al. · Nature Cell Biology · 2014 · 1.4K citations · Full text

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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

Xiang Gui, Hui Yang, Tuo Li et al. · Nature · 2019 · 1.3K citations · Full text

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Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1.1K citations · Full text

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