Identification of blood metabolites linked to the risk of cholelithiasis: a comprehensive Mendelian randomization study

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Jack Bowden, George Davey Smith, Philip Haycock et al. · Genetic Epidemiology · 2016 · 9.6K citations · Full text

Life Sciences, Biostatistics, Genetics +12

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Marie Verbanck, Chia‐Yen Chen, Benjamin M. Neale et al. · Nature Genetics · 2018 · 9.2K citations

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The MR-Base platform supports systematic causal inference across the human phenome

Gibran Hemani, Jie Zheng, Benjamin Elsworth et al. · eLife · 2018 · 8.4K citations · Full text

Life Sciences, Biostatistics, Genetics +16

MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data

Olena O Yavorska, Stephen Burgess · International Journal of Epidemiology · 2017 · 2.3K citations · Full text

Life Sciences, Biostatistics, Genetics +12

Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic

Jack Bowden, Fabiola Del Greco M, Cosetta Minelli et al. · International Journal of Epidemiology · 2016 · 1.7K citations · Full text

Public Health, Biostatistics, Genetics +13