Roles of <scp>FoxM1</scp>‐driven basal β‐cell proliferation in maintenance of β‐cell mass and glucose tolerance during adulthood

Abstract

Basal low-level proliferation of β-cells during adulthood is important for maintaining sufficient β-cell mass and good glucose tolerance and β-cell FoxM1 underlies this mechanism. Preserving β-cell FoxM1 activity may prevent the impairment of glucose tolerance with advancing age.