Concepedia

Publication | Open Access

Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer

DOIFull Paper Access

28

Citations

26

References

2022

Year

Craig Furman, Xiaoling Puyang, Zhaojie Zhang, Zhenhua J. Wu, Deepti Banka, Kiran Aithal, Lee A. Albacker, Ming‐Hong Hao, Sean Irwin, Amy Kim,
Molecular Cancer Therapeutics

Abstract

H3B-6545 is an ERα covalent antagonist that exhibits encouraging preclinical activity against CDK4/6i naïve and resistant ERαWT and ERαMUT tumors.

References

YearCitations

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