Cancer Cell · 2022 · 326 citations · 37 references
MedicineCancer BiologyOncologyBreast OncologyDrug DiscoveryMolecular OncologyBiomarker-guided Therapy SelectionCancer BiomarkersCancer Treatment PlanningHer2-positive Breast CancerMolecular Tumor ProfilingTargeted Cancer TherapyBreast Cancer Molecular SubtypesPersonalized Cancer TreatmentPredictive Biomarker DiscoveryPredictive BiomarkersPredictive PerformanceResponse Prediction ModelsTherapy Selection AlgorithmsTreatment Allocation
subsets (>15%). As new treatments are introduced, the subtyping schema determines the minimum response needed to show efficacy. This data platform provides an unprecedented resource and supports the usage of response-based subtypes to guide future treatment prioritization.
37
Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes
Joel S. Parker, Michael E. Mullins, Maggie C.U. Cheang et al. · Journal of Clinical Oncology · 2009 · 4.9K citations · Full text
Medicine, Bioinformatics, Oncology +16