Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies

Denise M. Wolf, Christina Yau, Julia Wulfkuhle, Lamorna Brown Swigart, Rosa I. Gallagher, Pei Rong Evelyn Lee, Zelos Zhu, Mark Jesus M. Magbanua, Rosalyn W. Sayaman, Nicholas O’Grady,

Cancer Cell · 2022 · 326 citations · 37 references

DOIFull text

Open access

Concepts

Abstract

subsets (>15%). As new treatments are introduced, the subtyping schema determines the minimum response needed to show efficacy. This data platform provides an unprecedented resource and supports the usage of response-based subtypes to guide future treatment prioritization.

References

37