Concepedia

Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity

Chiara Macchi, Annalisa Moregola, Maria Francesca Greco, Monika Svecla, Fabrizia Bonacina, Suveera Dhup, Rajesh K. Dadhich, Matteo Audano, Pierre Sonveaux, Claudio Mauro,

iScience · 2022 · 33 citations · 31 references

DOIFull text

Open access

Concepts

Abstract

T cells in the crosstalk with adipocytes and reinforce the concept that targeting immunometabolic reprogramming in lymphocyte could impact the immune-adipose tissue axis in obesity.

References

31

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.5K citations

, , +17

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Haiyan Xu, Glenn T. Barnes, Qing Yang et al. · Journal of Clinical Investigation · 2003 · 5.8K citations · Full text

, , +17

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Haiyan Xu, Glenn T. Barnes, Qing Yang et al. · Journal of Clinical Investigation · 2003 · 5.7K citations

, , +17

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Carey N. Lumeng, Jennifer L. Bodzin, Alan R. Saltiel · Journal of Clinical Investigation · 2007 · 4.6K citations · Full text

, , +17

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

Tauno Metsalu, Jaak Vilo · Nucleic Acids Research · 2015 · 3.9K citations · Full text

, , +17