6-methoxydihydroavicine, the alkaloid extracted from Macleaya cordata (Willd.) R. Br. (Papaveraceae), triggers RIPK1/Caspase-dependent cell death in pancreatic cancer cells through the disruption of oxaloacetic acid metabolism and accumulation of reactive oxygen species

Publication | Closed Access

DOI

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2022

Year

Nengfang Ma, Fugen Shangguan, Hongfei Zhou, Huimin Huang, Jun Lei, Jing An, Guihua Jin, Weiwei Zhuang, Shipeng Zhou, Shijia Wu,

Phytomedicine

Chemoprevention StrategyOncogenic AgentMedicineLipid PeroxidationApoptosisR. BrCell DeathPathologyPancreatic Cancer CellsOxaloacetic Acid MetabolismPharmacologyCancer ResearchOxidative Stress