Synthesis of 1,8‐Naphthyridine C‐Nucleosides and Their Base‐Pairing Properties in Oligodeoxynucleotides: Thermally Stable Naphthyridine:Imidazopyridopyrimidine Base‐Pairing Motifs

Abstract

Alt raus, Neu rein: Heck-Kupplungen machten die neuartigen 1,8-Naphthyridin-C-Nucleoside Na-NO und Na-ON (siehe Formeln) zugänglich. Oligodesoxynucleotide, die die Na-NO- und Na-ON-Nucleoside enthielten, bildeten mithilfe der Basenpaarungsmotive Na-NO:Im-ON und Na-ON:Im-NO äußerst stabile Duplexe. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2005/z461857_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.