Concepedia

Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3

Samuel Sidi, Takaomi Sanda, Richard D. Kennedy, Andreas T. Hagen, Cicely A. Jette, Raymond Hoffmans, Jennifer Pascual, Shintaro Imamura, Shuji Kishi, James F. Amatruda,

Cell · 2008 · 298 citations · 48 references

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48

ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

Shuhei Matsuoka, Bryan A. Ballif, Agata Smogorzewska et al. · Science · 2007 · 3.1K citations

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Requirement for p53 and p21 to Sustain G <sub>2</sub> Arrest After DNA Damage

Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science · 1998 · 2.8K citations

, , +17

A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

Jason Moffat, Dorre A. Grueneberg, Xiaoping Yang et al. · Cell · 2006 · 1.9K citations · Full text

, , +11

Chk1 is an essential kinase that is regulated by Atr and required for the G<sub>2</sub>/M DNA damage checkpoint

Qinghua Liu, Saritha Guntuku, Xian-Shu Cui et al. · Genes & Development · 2000 · 1.6K citations · Full text

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Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM

Ian Hickson, Yan Zhao, Caroline J. Richardson et al. · Cancer Research · 2004 · 1.2K citations

, , +16