James F. Amatruda

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

Baozhi Chen, Michael Dodge, Wei‐Jen Tang et al. · Nature Chemical Biology · 2009 · 1.4K citations · Full text

Signal Transduction, Signaling Pathway, Medicine +9

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

Bao Nguyen Puente, Wataru Kimura, Shalini Muralidhar et al. · Cell · 2014 · 868 citations · Full text

Genome Instability, Cardiomyopathy, Dna Damage +10

BRAF Mutations Are Sufficient to Promote Nevi Formation and Cooperate with p53 in the Genesis of Melanoma

E. Elizabeth Patton, Hans R. Widlund, Jeffery L. Kutok et al. · Current Biology · 2005 · 665 citations · Full text

Tumor Biology, Nevi Formation, Braf Mutations +8

Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3

Samuel Sidi, Takaomi Sanda, Richard D. Kennedy et al. · Cell · 2008 · 295 citations · Full text

Dna Damage, Cell Regulation, Apoptosis +8

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

Enrico Moro, Günes Özhan, Alessandro Mongera et al. · Developmental Biology · 2012 · 255 citations

Systems Biology, Signal Transduction, Vivo Wnt +7