Synthesis of dicationic diarylpyridines as nucleic-acid binding agents

The search for structure-specific nucleic acid-interactive drugs: Effects of compound structure on RNA versus DNA interaction strength

W. David Wilson, Lynda Ratmeyer, Min Zhao et al. · Biochemistry · 1993 · 407 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Binding of 4',6-diamidino-2-phenylindole (DAPI) to GC and mixed sequences in DNA: intercalation of a classical groove-binding molecule

W. David Wilson, Farial A. Tanious, H. Bartoń et al. · Journal of the American Chemical Society · 1989 · 147 citations

Life Sciences, Biology, Molecular Biology +12

Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans

Bijan Das, David W. Boykin · Journal of Medicinal Chemistry · 1977 · 142 citations

Natural Sciences, Chemistry, Pharmacology +13

Syntheses Using the Michael Adddition of Phridinium Salts

Fritz Kröhnke, Wilfried Zecher, Jürgen Curtze et al. · Angewandte Chemie International Edition in English · 1962 · 134 citations

Natural Sciences, Chemistry, Green Chemistry +10

A convenient synthesis of nitriles from primary amides under mild conditions

Francesco Campagna, Andrea Carotti, G. Casini · Tetrahedron Letters · 1977 · 126 citations

Natural Sciences, Chemistry, Medicinal Chemistry +4