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Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors

Medicinal ChemistryBioorganic ChemistryBiochemistryPotent Histone DeacetylaseMedicine-Thiophene-2-hydroxamic AcidsNatural SciencesRational Drug DesignPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyInhibitory ActivityDrug Discovery