Antimicrobial Agents and Chemotherapy · 2005 · 39 citations · 15 references
PharmacyInfectious DiseasesMicrobiologyAntimicrobial PharmacotherapyMedical MicrobiologyMicrobial PathogenesisAntibacterial PharmacologyAntimicrobial TherapyBacterial InfectionsCombination Antimicrobial TherapyDrug Interactions With AntimicrobialsEmpiric Antimicrobial TherapyCombination Therapy EvaluationNecrotizing FasciitisNecrotizing InfectionsTime-kill AssaysTime-kill KineticsVibrio Infections
We performed time-kill studies of antimicrobial combinations that included minocycline, cefotaxime, and ciprofloxacin with Vibrio vulnificus ATCC 27562. Cefotaxime-plus-ciprofloxacin combinations acted synergistically against V. vulnificus in vitro, and this combination regimen can be a good choice as the empirical treatment for suspected necrotizing fasciitis due to V. vulnificus.
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Disease Caused by a Marine Vibrio
Paul A. Blake, Michael Merson, Robert E. Weaver et al. · New England Journal of Medicine · 1979 · 632 citations
Syndromes of <i>Vibrio vulnificus</i> Infections
Karl C. Klontz · Annals of Internal Medicine · 1988 · 405 citations