Magnetically Triggered Dual Functional Nanoparticles for Resistance‐Free Apoptotic Hyperthermia

Abstract

Gegen jeden Widerstand: Wärmebehandelte Krebszellen haben einen schützenden Resistenz- und Überlebensmechanismus. Resistenzfreie Zelltod-induzierende magnetische Nanopartikel (RAINs) fördern den hyperthermalen Zelltod, indem sie die Wärmeerzeugung und das Freisetzen von Geldanamycin (GM) zur Hemmung des Hitzschockproteins (Hsp) in einem magnetischen Wechselfeld (AMF) einleiten (siehe Bild) und somit das Überleben der Zelle hindern. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.