Annual Review of Immunology · 1988 · 218 citations · 0 references
Life SciencesImmunologyOncologyImmunopathologyNeoplasiaTumor ProgressionCancer ImmunotherapyCell-mediated ImmunityCytotoxic T Lymphocyte ResponsesT Cell BiologyT Cell DifferentiationT Cell Responses To TumorsAnimal Disease ModelsC1 InhibitorCd8 Positive T Cell DifferentiationCd8 Positive T CellsCd8 T Cell ActivationCd8+ Tumor-infiltrating LymphocytesInhibitory Molecule ExpressionT Cell-mediated Pathology
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More